The 'Second Factor' of tachycardia-induced atrial remodeling

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Angiotensin-(1–7) attenuates atrial tachycardia-induced sympathetic nerve remodeling

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Importance of refractoriness heterogeneity in the enhanced vulnerability to atrial fibrillation induction caused by tachycardia-induced atrial electrical remodeling.

BACKGROUND Rapid atrial activation causes electrical remodeling that promotes the occurrence and the maintenance of atrial fibrillation (AF). Although remodeling has been shown to alter electrophysiological variables, the spatial uniformity of these changes is unknown. METHODS AND RESULTS Dogs subjected to rapid atrial pacing (400 bpm) for 24 hours (n=12) were compared with sham-operated dogs...

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ژورنال

عنوان ژورنال: Cardiovascular Research

سال: 2000

ISSN: 0008-6363

DOI: 10.1016/s0008-6363(00)00067-5